I've experienced the same symptoms (mouse and need for hard reset).
It looks like it's solved now.
Win 10, P3dv3 Pro, no addons
1 Device Manager, Saitek trim wheel connected.
2 Device Manager lists wheel as Saitek Pro Flight Cessna trim wheel device (Driver 18.104.22.168) (2009)
3 Saitek wheel device uninstall driver (+delete files)
(however, after a disconnect and reconnect I believe the driver came back; maybe from windows online)
4 disconnect and reconnect
5 If Saitek driver shows again, Device manager rollback driver ->generic microsoft driver afterwards
6 Verify that Device manager does not show any Saitek USB devices as Saitek Wheel (et.c.)
(The will be listed as generic USB Input and HID Compliant ...)
6.5 Disconnect and reconnect
7 Verify under Devices & Printers (not device manager) that it still shows as "Pro Flight Cessna Trim Wheel".
"Pro Flight Cessna Trim Wheel" properties / Hardware shows 2 devices:
Hid Compliant Game Controller & USB Input device
Manufacturer for both devices: Standard System Device
7.5. This may be optional: In device manager, I disabled "Windows can turn off power" for all USB Input devices -
I don't think it made any difference to the issue and probably will revert that in the future.
8 Start P3D, wheel should be selectable in Controller dialog
The wheel seemed fairly stable in P3D after that.
(Still having stability issues with thrust dropping out on take off with Saitek throttle quadrant though)
Win 10, P3dV3 Pro, Aerosoft Airbus 320/321 1.31, FTX Global 1.40/Vector 1.30/openLCEurope 1.20
Ch Pedals, Saitek Pro wheel, throttle quadrant, Multi panel, Radio panel
I7 4GHZ, 16GB, GTX980, SSD, single screen 50 inch 4k